A great street for adventurers looking to start their evenings off with a beer or six is the Avenida das Rendeiras, a popular area in Lagoa da Conceicao on the eastern part of the island. On one side of the road, you have the beach; on the other, one of the highest saturations of nightlife in Florianopolis. Some of the most popular include the pub-themed John Bull Pub, where you can grab a beer and listen to live rock music with a somewhat older crowd; Chico's Music Bar, which plays a lot of samba and other Brazilian favorites; and a number of worthwhile (although relatively expensive) dives meant to attract a younger crowd. A great area to hang out and enjoy your happy hour as the sun goes down, Avenida das Rendeiras also serves in close proximity to Joaquina Beach and other beach-going activities that may exist in your Florianopolis itinerary.
Note:There are also a number of eateries and bars at and around the Shopping da Lagoa mall, located at the western end of the Avenida das Reinderas. Enjoy the outdoor seating and the cafe vibe of the area.