In such a multicultural city, it's no surprise that the attractions to be found downtown would follow suit. From the McGill University campus to the popular nightlife street of Saint-Laurent, there is plenty to see, do, and eat in view of skyscrapers and the lovely Mont-Royal. While there are plenty of museums and other highly cultural excursions, you may find yourself most-fully immersed in the ever-plentiful food and nightlife on tap downtown.
There are two streets that stand out most for nightlife-lovers: Saint-Catherine and Crescent. Saint-Catherine, which runs parallel to the river northeast out of downtown, may be the most popular tourist street in the city and is home to innumerable nightclubs, bars, and much more. Two of the cities most popular persuasions can be found at both ends of this street; local microbrews can be found at a number of the establishments where it crosses rue Peel (Dominion Square Tavern is great), while gay dance clubs crowd the northeastern end of the street and superclubs like Stereo and Circus lie between. Crescent, near McGill University, is all upscale drinking and dining. Modern pubs with outdoor seating are big here, with institutions like Hurley's Irish pub leading the pack. Just be wary of the cost of drinking here; it can add up.
for cheaper dining options, there is plenty to explore along Avenue St. Denis near where it intersects with Saint-Catherine; if cafe food, pizza, and fast food are your style then you'll be satisfied. Also, great Asian cuisine can be had at rue de la Gauchetière and the pedestrianized streets nearby known as the local Chinatown.