In the midst of Royal Natal National Park (marked on some maps as the Ukahlamba Drakensberg World Heritage Site) lies the world's second biggest waterfall, plummeting 948 meters (3,110 feet) to the forest floor. It is a gorgeous spectacle, dropping in five cascades through the Drakensberg Amphitheater, a truly impressive 5 kilometer (about 3 miles) long cliff face.
Your best bet for a spectacular view is the Mount-Aux-Sources hiking route, a 5-8 hour hike that will bring you to the top of the falls. If you're hiking in the spring, you may need a bathing suit, for there are a few heavy river crossings and a water-filled tunnel to be crossed before reaching the top, making for quite an adventure. If you want the best look at the falls themselves, The Tugela Gorge Trail will lead you into the valley below. There are other hiking trails worth pursuing and lodging in the park for overnight stays (Mahai Camp, Thendele Lodge), so pay your $2 USD (per day) for entrance and stay awhile.
Note:Royal Natal National Park can be reached via the N3 from Durban (4 hour drive) or pretty much anywhere else in the region.